Bio-research

Bio-research

Bringing the laser to a cell or a patient body part in a safe and user-friendly manner remains one of the commodities that is highly  sought after by surgeons and biologists. GLO Kagome fiber and its functionalised form PMC is well suited to offer a laser delivery link to any cells or body part with exceptional combination of flexibility, low transmission optical loss, low pulse distortion, and access to very small and inconspicuous spaces to machine. GLO's current experience with players in the bio-medical sector is an asset that it offers to end-users or medical machine manufacturers in developing innovative fiber laser tools for surgery and bio-medical applications. Furthermore, GLO can help in developing specific lasers, which are now used in a variety of medical treatments across a range of visible wavelengths. For example lasers with high power operating at specific wavelengths in the yellow part of the spectrum can be used to treat a variety of blood vessel disorders such as removal of unwanted leg veins and facial capillaries. There are also applications in opthalamology, for example for treating the detachment of the retina.
Through its unique solutions for laser beam delivery and laser frequency conversion, GLO technology can address most of the bio-photonic applications such as cytometry, imaging, DNA sequencing or forensics.
Flow cytometry is a technique that is used to analyse thousands of microscopic particles, such as cells every second, and which can also isolate particles with specific properties. The technique is being increasingly used for diagnosing health disorders, such as blood cancers. Modern flow cytometers contain multiple lasers with visible wavelengths. The lasers currently used do not exactly match the excitation wavelengths of the dyes and the systems are typically expensive and bulky. GLO technology can provide a multi-line laser source which exactly matches a number of the dye wavelengths at high power which is also compact and low cost and would have a significant impact in this field.
Research Based Bio-imaging uses Lasers extensively in a number of bio-imaging techniques, such as confocal microscopy, multiphoton microscopy and photoacoustic imaging. GLO technology can be used to provide an alternative to existing products for these techniques as well as opening up new opportunities with the generation of wavelengths previously unachievable with products on the market.
DNA Sequencing. The DNA sequencing is growing rapidly with developments in the speed of sequencing towards personalised medicine. Visible lasers around the wavelengths of key fluorescent dyes are a key part of the microarray scanners which are used in sequencing. Closer matching of lasers to the dye wavelengths has the potential to reduce the overall laser power applied to the sample and give clearer results. GLO laser frequency conversion technology is an excellent candidate for development of such lasers.
Forensics. Forensic systems use lasers to detect latent fingerprints and trace evidence at defined wavelengths in the visible. Current solutions for this are bulky and expensive. The PMC has the potential to offer a low cost, hand-held compact solution for forensic analysis.

 

On the right you will find some representative literature on "Bio-research" topics.